Charlotte's unseen parents were first mentioned in the television episode "Parents".
According to Charlotte and her grandmother Charlene, Charlotte's parents are astronauts on a space station. In the episode "Parents", Vendetta makes two fiend look-a-likes to impersonate Charlotte's parents. In the end of the episode, the fiends are eaten by a whale, and Grudge is about to shoot Charlotte with another fiend, but misses, firing into the sky. Charlotte sees the contrail left by the fiend and thinks her parents have returned to the space station.